ERG3

Sterol C-5 desaturase
Identifiers
OrganismSaccharomyces cerevisiae
SymbolERG3
Alt. symbolsSC5D, SYR1
Entrez850745
HomoloGene5044
RefSeq (mRNA)NM_001181943
Other data
EC number1.14.19.20
ChromosomeXII: 0.25 - 0.25 Mb

ERG3 or sterol C-5 desaturase is a fungal enzyme originally from Saccharomyces cerevisiae, the human ortholog of ERG3 is SC5D. ERG3 localizes to both the endoplasmic reticulum and vesicles, catalyzes the C5(6)-dehydrogenation of episterol to 5-dehydroepisterol, 5-Dehydroepisterol will be further converted into ergosterol.