EVI5L

EVI5L
Identifiers
Aliases	EVI5L, ecotropic viral integration site 5 like
External IDs	HomoloGene: 71934; GeneCards: EVI5L; OMA:EVI5L - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	7,864,976 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; right frontal lobe; ; cingulate gyrus; ; anterior cingulate cortex; ; Amygdala; ; C1 segment; ; Hypothalamus; ; Brodmann area 9; ; substantia nigra; ; putamen;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; GTPase activator activity;
Cellular component	endomembrane system; intracellular anatomical structure; membrane; integral component of membrane;
Biological process	negative regulation of cilium assembly; activation of GTPase activity; intracellular protein transport; regulation of vesicle fusion; positive regulation of GTPase activity; regulation of GTPase activity;
	Sources:Amigo / QuickGO
Orthologs
	115704
	n/a
	ENSG00000142459
	n/a
	Q96CN4
	n/a
	NM_001159944; NM_145245
	n/a
	NP_001153416; NP_660288
	n/a
	Wikidata
View/Edit Human

EVI5L (Ecotropic Viral Integration Site 5-Like) is a protein that in humans is encoded by the EVI5L gene. EVI5L is a member of the Ras superfamily of monomeric guanine nucleotide-binding (G) proteins, and functions as a GTPase-activating protein (GAP) with a broad specificity. Measurement of in vitro Rab-GAP activity has shown that EVI5L has significant Rab2A- and Rab10-GAP activity.