RNA-binding protein EWS

EWSR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2CPE
Identifiers
Aliases	EWSR1, EWS, bK984G1.4, EWS-FLI1, Ewing sarcoma breakpoint region 1, EWS RNA binding protein 1
External IDs	OMIM: 133450; MGI: 99960; HomoloGene: 136069; GeneCards: EWSR1; OMA:EWSR1 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	29,300,525 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	5,099,266 bp
RNA expression pattern
	Top expressed in
	right uterine tube; ; left testis; ; right testis; ; right hemisphere of cerebellum; ; right lobe of thyroid gland; ; right adrenal cortex; ; left adrenal cortex; ; ganglionic eminence; ; body of uterus; ; left lobe of thyroid gland;
	Top expressed in
	yolk sac; ; neural layer of retina; ; ventricular zone; ; genital tubercle; ; tail of embryo; ; superior frontal gyrus; ; primary visual cortex; ; spermatocyte; ; spermatid; ; lip;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	metal ion binding; protein binding; calmodulin binding; identical protein binding; nucleic acid binding; RNA binding;
Cellular component	cytoplasm; plasma membrane; nucleolus; membrane; nucleus;
Biological process	regulation of transcription, DNA-templated; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	2130
	14030
	ENSG00000182944
	ENSMUSG00000009079
	Q01844
	Q61545
	NM_001163285; NM_001163286; NM_001163287; NM_005243; NM_013986
	NM_001283061; NM_001283062; NM_001283063; NM_007968
	NP_001156757; NP_001156758; NP_001156759; NP_005234; NP_053733
NP_001269990; NP_001269991; NP_001269992; NP_031994; NP_001349541;
	NP_001349542; NP_001349543; NP_001349544; NP_001349545; NP_001349546; NP_001349547; NP_001349549
	Wikidata
View/Edit Human	View/Edit Mouse

RNA-binding protein EWS is a protein that in humans is encoded by the EWSR1 gene on human chromosome 22, specifically 22q12.2. It is one of 3 proteins in the FET protein family.