Eyes absent homolog 2

EYA2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3GEB, 3HB0, 3HB1, 4EGC
Identifiers
Aliases	EYA2, EAB1, EYA transcriptional coactivator and phosphatase 2
External IDs	OMIM: 601654; MGI: 109341; HomoloGene: 40711; GeneCards: EYA2; OMA:EYA2 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	47,188,844 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	165,613,647 bp
RNA expression pattern
	Top expressed in
	olfactory zone of nasal mucosa; ; Achilles tendon; ; parotid gland; ; mucosa of esophagus; ; nasal epithelium; ; mucosa of paranasal sinus; ; right uterine tube; ; minor salivary glands; ; tibial nerve; ; mucosa of transverse colon;
	Top expressed in
	nasal placode; ; cranial nervi; ; vagus nerve; ; accessory nerve; ; optic recess; ; Jacobson's organ; ; lip; ; epithelium of stomach; ; genital tubercle; ; glossopharyngeal nerve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	phosphoprotein phosphatase activity; metal ion binding; protein binding; protein tyrosine phosphatase activity; hydrolase activity; magnesium ion binding; transcription factor binding;
Cellular component	cytoplasm; nucleoplasm; mitochondrion; nucleus; cytosol;
Biological process	striated muscle tissue development; regulation of transcription, DNA-templated; protein dephosphorylation; transcription, DNA-templated; cellular response to DNA damage stimulus; multicellular organism development; extrinsic apoptotic signaling pathway in absence of ligand; mesodermal cell fate specification; mitochondrial outer membrane permeabilization; positive regulation of DNA repair; peptidyl-tyrosine dephosphorylation; DNA repair; negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; chromatin organization; anatomical structure development;
	Sources:Amigo / QuickGO
Orthologs
	2139
	14049
	ENSG00000064655
	ENSMUSG00000017897
	O00167
	O08575
	NM_005244; NM_172110; NM_172111; NM_172112; NM_172113
	NM_001271962; NM_001271963; NM_010165
	NP_005235; NP_742108
	NP_001258891; NP_001258892; NP_034295
	Wikidata
View/Edit Human	View/Edit Mouse

Eyes absent homolog 2 is a protein that in humans is encoded by the EYA2 gene.