EZH1

EZH1
Identifiers
Aliases	EZH1, KMT6B, enhancer of zeste 1 polycomb repressive complex 2 subunit
External IDs	OMIM: 601674; MGI: 1097695; HomoloGene: 20458; GeneCards: EZH1; OMA:EZH1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	42,745,049 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	101,117,289 bp
RNA expression pattern
	Top expressed in
	cerebellar hemisphere; ; right hemisphere of cerebellum; ; tibial nerve; ; dorsal motor nucleus of vagus nerve; ; Achilles tendon; ; left ovary; ; sural nerve; ; olfactory bulb; ; right ovary; ; canal of the cervix;
	Top expressed in
	ciliary body; ; iris; ; motor neuron; ; retinal pigment epithelium; ; ankle; ; zygote; ; vestibular membrane of cochlear duct; ; dentate gyrus of hippocampal formation granule cell; ; granulocyte; ; neural layer of retina;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; chromatin binding; histone-lysine N-methyltransferase activity; DNA-binding transcription factor activity, RNA polymerase II-specific; DNA binding; transcription corepressor activity;
Cellular component	ESC/E(Z) complex; nucleus; nucleoplasm; telomere;
Biological process	histone H3-K27 methylation; anatomical structure morphogenesis; methylation; regulation of transcription, DNA-templated; hippocampus development; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; chromatin organization; negative regulation of transcription by RNA polymerase II; chromatin remodeling;
	Sources:Amigo / QuickGO
Orthologs
	2145
	14055
	ENSG00000108799
	ENSMUSG00000006920
	Q92800
	P70351
	NM_001991; NM_001321079; NM_001321081; NM_001321082
	NM_007970
	NP_001308008; NP_001308010; NP_001308011; NP_001982
NP_031996; NP_001390736; NP_001390738; NP_001390739; NP_001390740;
	NP_001390741; NP_001390742; NP_001390743; NP_001390744; NP_001390745; NP_001390747; NP_001390750; NP_001390751
	Wikidata
View/Edit Human	View/Edit Mouse

Histone-lysine N-methyltransferase EZH1 is an enzyme that in humans is encoded by the EZH1 gene.