Endocardial cushions
| Endocardial cushions | |
|---|---|
| Details | |
| Carnegie stage | 14 |
| Days | 27 |
| Precursor | Lateral plate mesoderm |
| Gives rise to | Septum intermedium |
| Identifiers | |
| Latin | tubera endocardiaca atrioventricularia |
| MeSH | D054089 |
| TE | cushions_by_E5.11.1.6.0.0.4 E5.11.1.6.0.0.4 |
| Anatomical terminology | |
Endocardial cushions, or atrioventricular cushions, refer to a subset of cells in the development of the heart that play a vital role in the proper formation of the heart septa.
They develop on the atrioventricular canal and conotruncal region of the bulbus cordis.
During heart development, the heart starts out as a tube. As heart development continues, this tube undergoes remodeling to eventually form the four-chambered heart. The endocardial cushions are a subset of cells found in the developing heart tube that will give rise to the heart's primitive valves and septa, critical to the proper formation of a four-chambered heart.