Endothelin receptor

endothelin receptor type A
Identifiers
SymbolEDNRA
NCBI gene1909
HGNC3179
OMIM131243
RefSeqNM_001957
UniProtP25101
Other data
LocusChr. 4 q31.2
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StructuresSwiss-model
DomainsInterPro
endothelin receptor type B
Identifiers
SymbolEDNRB
Alt. symbolsHSCR2, HSCR
NCBI gene1910
HGNC3180
OMIM131244
RefSeqNM_000115
UniProtP24530
Other data
LocusChr. 13 q22
Search for
StructuresSwiss-model
DomainsInterPro

There are at least four known endothelin receptors, ETA, ETB1, ETB2 and ETC, all of which are G protein-coupled receptors whose activation result in elevation of intracellular-free calcium, which constricts the smooth muscles of the blood vessels, raising blood pressure, or relaxes the smooth muscles of the blood vessels, lowering blood pressure, among other functions.

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