Acute erythroid leukemia

Acute erythrocyte leukemia
Other namesDi Guglielmo syndrome
Bone marrow smear from a case of erythroleukemia
SpecialtyHematology, oncology

Acute erythrocyte leukemia (AEL) is an extremely rare form of acute myeloid leukemia (less than 1% of AML cases) which is characterized by neoplastic proliferation of erythroid cells with features of maturation arrest (increased erythroblasts) and high prevalence of biallelic TP53 alterations. It is defined as type "M6" under the FAB classification.

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