Erythrose 4-phosphate
| Names | |
|---|---|
| IUPAC names
[(2R,3R)-2,3-Dihydroxy-4-oxobutyl] phosphate d-Erythrose 4-(dihydrogen phosphate) | |
| Other names
E4P | |
| Identifiers | |
3D model (JSmol) |
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| ChEBI | |
| ChemSpider | |
| MeSH | erythrose+4-phosphate |
PubChem CID |
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| UNII | |
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| Properties | |
| C4H9O7P | |
| Molar mass | 200.084 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references | |
Erythrose 4-phosphate is a phosphate of the simple sugar erythrose. It is an intermediate in the pentose phosphate pathway and the Calvin cycle.
The enzyme transaldolase catalyzes the formation of erythrose 4-phosphate and fructose 6-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate. This reaction is a part of the non-oxidative phase of the pentose phosphate pathway.
In the Calvin cycle, the enzyme fructose-bisphosphate aldolase catalyzes the formation of sedoheptulose 1,7-bisphosphate from erythrose 4-phosphate and dihydroxyacetone phosphate.
In addition, it serves as a precursor in the biosynthesis of the aromatic amino acids tyrosine, phenylalanine, and tryptophan. It is used in the first step of the shikimate pathway. At this stage, phosphoenolpyruvate and erythrose-4-phosphate react to form 3-deoxy-D-arabinoheptulosonate-7-phosphate (DAHP), in a reaction catalyzed by the enzyme DAHP synthase.
It also used in 3-hydroxy-1-aminoacetone phosphate biosynthesis, which is a precursor of vitamin B6 in DXP-dependent pathway. Erythrose-4-phosphate dehydrogenase is used to produce erythronate-4-phosphate.