Estradiol enantate/algestone acetophenide

< Estradiol enantate
Estradiol enantate /
algestone acetophenide
Combination of
Estradiol enantateEstrogen
Algestone acetophenideProgestogen
Clinical data
Trade namesPerlutal, Topasel, Unalmes, Yectames, many others
Other namesEstradiol enantate/dihydroxy­progesterone acetophenide; E2-EN/DHPA
Routes of
administration
Intramuscular injection
Identifiers
CAS Number
PubChem CID
UNII

Estradiol enantate/algestone acetophenide, also known as estradiol enantate/dihydroxyprogesterone acetophenide (E2-EN/DHPA) and sold under the brand names Perlutal and Topasel among others, is a form of combined injectable birth control which is used to prevent pregnancy. It contains estradiol enantate (E2-EN), an estrogen, and algestone acetophenide (dihydroxyprogesterone acetophenide; DHPA), a progestin. The medication is given once a month by injection into muscle.

E2-EN/DHPA is used widely throughout Latin America, is also marketed in Hong Kong, and was previously available in Portugal and Spain as well but was discontinued in these countries.