FAM13B

FAM13B
Identifiers
Aliases	FAM13B, ARHGAP49, C5orf5, FAM13B1, KHCHP, N61, family with sequence similarity 13 member B
External IDs	OMIM: 609371; MGI: 2447834; HomoloGene: 9585; GeneCards: FAM13B; OMA:FAM13B - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	138,051,961 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	34,639,884 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; germinal epithelium; ; tail of epididymis; ; palpebral conjunctiva; ; seminal vesicula; ; Brodmann area 23; ; parietal pleura; ; sural nerve; ; visceral pleura; ; endothelial cell;
	Top expressed in
	tail of embryo; ; substantia nigra; ; facial motor nucleus; ; motor neuron; ; genital tubercle; ; lateral hypothalamus; ; paraventricular nucleus of hypothalamus; ; dorsomedial hypothalamic nucleus; ; ventral tegmental area; ; medullary collecting duct;
	More reference expression data
	n/a
Gene ontology
Molecular function	GTPase activator activity;
Cellular component	cytosol;
Biological process	positive regulation of GTPase activity; regulation of small GTPase mediated signal transduction; signal transduction;
	Sources:Amigo / QuickGO
Orthologs
	51306
	225358
	ENSG00000031003
	ENSMUSG00000036501
	Q9NYF5
	Q8K2H3
	NM_001101800; NM_001101801; NM_016603
	NM_146084
	NP_001095270; NP_001095271; NP_057687
	NP_666196
	Wikidata
View/Edit Human	View/Edit Mouse

Family with sequence similarity 13 member B is a protein which in humans is encoded by the FAM13B gene, also known as C5ORF5. The FAM13B gene is found in vertebrates and jawed fish. FAM13B is expressed ubiquitously in human tissues and has been linked to maglinant myelomas susceptibility to atrial fibrillation, a cardiac arrhythmia.