FAM98A

FAM98A
Identifiers
Aliases	FAM98A, family with sequence similarity 98 member A
External IDs	MGI: 1919972; HomoloGene: 41042; GeneCards: FAM98A; OMA:FAM98A - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	33,599,347 bp
Gene location (Mouse)
Chr.	Chromosome 17 (mouse)
End	75,858,941 bp
RNA expression pattern
	Top expressed in
	tibia; ; male germ cell; ; sperm; ; smooth muscle tissue; ; Pons; ; inferior ganglion of vagus nerve; ; right ventricle; ; biceps brachii; ; endothelial cell; ; Epithelium of choroid plexus;
	Top expressed in
	saccule; ; otic placode; ; otic vesicle; ; lacrimal gland; ; cumulus cell; ; parotid gland; ; pituitary gland; ; seminiferous tubule; ; dermis; ; primitive streak;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; RNA binding; protein methyltransferase activity;
Cellular component	tRNA-splicing ligase complex;
Biological process	protein methylation; positive regulation of cell population proliferation; positive regulation of gene expression; lysosome localization; positive regulation of ruffle assembly;
	Sources:Amigo / QuickGO
Orthologs
	25940
	72722
	ENSG00000119812
	ENSMUSG00000002017
	Q8NCA5
	Q3TJZ6
	NM_015475; NM_001304538
	NM_133747; NM_001357860
	NP_001291467; NP_056290; NP_001291467.1; NP_056290.3
	NP_598508; NP_001344789
	Wikidata
View/Edit Human	View/Edit Mouse

Family with sequence similarity 98, member A, or FAM98A, is a gene that in the human genome encodes the FAM98A protein. FAM98A has two paralogs in humans, FAM98B and FAM98C. All three are characterized by DUF2465, a conserved domain shown to bind to RNA. FAM98A is also characterized by a glycine-rich C-terminal domain. FAM98A also has homologs in vertebrates and invertebrates and has distant homologs in choanoflagellates and green algae.