FAT4

FAT4
Identifiers
Aliases	FAT4, CDHF14, CDHR11, FAT-J, FATJ, NBLA00548, VMLDS2, HKLLS2, FAT atypical cadherin 4
External IDs	OMIM: 612411; MGI: 3045256; HomoloGene: 14377; GeneCards: FAT4; OMA:FAT4 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	125,492,932 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	39,066,134 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; stromal cell of endometrium; ; periodontal fiber; ; epithelium of colon; ; mucosa of paranasal sinus; ; Descending thoracic aorta; ; popliteal artery; ; tibial arteries; ; ventricular zone; ; tibia;
	Top expressed in
	hand; ; internal carotid artery; ; external carotid artery; ; Gonadal ridge; ; dermis; ; vas deferens; ; conjunctival fornix; ; human fetus; ; ascending aorta; ; condyle;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; calcium ion binding;
Cellular component	integral component of membrane; apical part of cell; membrane; intracellular anatomical structure; plasma membrane; extracellular exosome;
Biological process	cerebral cortex development; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; homophilic cell adhesion via plasma membrane adhesion molecules; neurogenesis; heart morphogenesis; regulation of metanephric nephron tubule epithelial cell differentiation; kidney development; plasma membrane organization; digestive tract development; inner ear receptor cell stereocilium organization; ossification involved in bone maturation; hippo signaling; branching involved in ureteric bud morphogenesis; cell adhesion; nephron development; fibroblast growth factor receptor signaling pathway; Notch signaling pathway; condensed mesenchymal cell proliferation; cell-cell adhesion;
	Sources:Amigo / QuickGO
Orthologs
	79633
	329628
	ENSG00000196159
	ENSMUSG00000046743
	Q6V0I7
	Q2PZL6
	NM_001291285; NM_001291303; NM_024582
	NM_183221
	NP_001278214; NP_001278232; NP_078858; NP_001278214.1; NP_001278232.1
	NP_899044
	Wikidata
View/Edit Human	View/Edit Mouse

Protocadherin Fat 4, also known as cadherin family member 14 (CDHF14) or FAT tumor suppressor homolog 4 (FAT4), is a protein that in humans is encoded by the FAT4 gene.

FAT4 is associated with the Hippo signaling pathway.