FAT1

FAT1
Identifiers
Aliases	FAT1, CDHF7, CDHR8, FAT, ME5, hFat1, FAT atypical cadherin 1
External IDs	OMIM: 600976; MGI: 109168; HomoloGene: 66302; GeneCards: FAT1; OMA:FAT1 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	186,726,722 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	45,505,294 bp
RNA expression pattern
	Top expressed in
	Epithelium of choroid plexus; ; tibia; ; metanephric glomerulus; ; periodontal fiber; ; ventricular zone; ; cartilage tissue; ; stromal cell of endometrium; ; jejunal mucosa; ; mucosa of colon; ; mucosa of sigmoid colon;
	Top expressed in
	hand; ; ciliary body; ; stroma of bone marrow; ; iris; ; molar; ; cumulus cell; ; medullary collecting duct; ; calvaria; ; renal corpuscle; ; conjunctival fornix;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	calcium ion binding; protein binding;
Cellular component	cytoplasm; integral component of membrane; membrane; cell-cell junction; focal adhesion; filopodium; plasma membrane; integral component of plasma membrane; cell junction; perinuclear region of cytoplasm; extracellular exosome; nucleus; lamellipodium; apical plasma membrane;
Biological process	actin filament organization; cell-cell signaling; anatomical structure morphogenesis; establishment or maintenance of cell polarity; cell adhesion; cell migration; homophilic cell adhesion via plasma membrane adhesion molecules; cell-cell adhesion; epithelial cell morphogenesis; establishment or maintenance of epithelial cell apical/basal polarity; camera-type eye morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	2195
	14107
	ENSG00000083857
	ENSMUSG00000070047
	Q14517
	n/a
	NM_005245
	NM_001081286; NM_010179
	NP_005236
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Protocadherin FAT1 is a protein that in humans is encoded by the FAT1 gene.