FBXO24

FBXO24
Identifiers
AliasesFBXO24, FBX24, F-box protein 24
External IDsOMIM: 609097; MGI: 1918426; HomoloGene: 14131; GeneCards: FBXO24; OMA:FBXO24 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

26261

71176

Ensembl

ENSG00000106336

ENSMUSG00000089984

UniProt

O75426

Q9D417

RefSeq (mRNA)

NM_001163499
NM_012172
NM_033506

NM_027708

RefSeq (protein)

NP_001156971
NP_036304
NP_277041

NP_081984

Location (UCSC)Chr 7: 100.58 – 100.6 MbChr 5: 137.61 – 137.63 Mb
PubMed search
Wikidata
View/Edit HumanView/Edit Mouse

F-box only protein 24 is a protein that in humans is encoded by the FBXO24 gene.

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates two transcript variants.