FBXO4

FBXO4
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3L2O, 3L82
Identifiers
Aliases	FBXO4, FBX4, F-box protein 4
External IDs	OMIM: 609090; MGI: 2146220; HomoloGene: 8134; GeneCards: FBXO4; OMA:FBXO4 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	41,941,743 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	4,009,055 bp
RNA expression pattern
	Top expressed in
	Achilles tendon; ; body of pancreas; ; testicle; ; gastric mucosa; ; right uterine tube; ; skin of arm; ; tibial nerve; ; right lobe of thyroid gland; ; right lobe of liver; ; left lobe of thyroid gland;
	Top expressed in
	saccule; ; ciliary body; ; proximal tubule; ; otic vesicle; ; right kidney; ; subcutaneous adipose tissue; ; white adipose tissue; ; spermatocyte; ; duodenum; ; calvaria;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; protein homodimerization activity; ubiquitin protein ligase activity; ubiquitin-protein transferase activity;
Cellular component	ubiquitin ligase complex; cytosol; SCF ubiquitin ligase complex; cytoplasm;
Biological process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; telomere maintenance; positive regulation of protein ubiquitination; ubiquitin-dependent protein catabolic process; protein polyubiquitination; common myeloid progenitor cell proliferation; protein destabilization; positive regulation of protein polyubiquitination; ageing; negative regulation of fibroblast proliferation; cellular response to ionizing radiation; cellular homeostasis; regulation of DNA damage checkpoint; negative regulation of protein localization to nucleus; posttranscriptional regulation of gene expression; protein ubiquitination; regulation of protein stability; positive regulation of telomere maintenance via telomerase; post-translational protein modification;
	Sources:Amigo / QuickGO
Orthologs
	26272
	106052
	ENSG00000151876
	ENSMUSG00000022184
	Q9UKT5
	Q8CHQ0
	NM_001297437; NM_012176; NM_033484
	NM_134099
	NP_001284366; NP_036308; NP_277019
	NP_598860
	Wikidata
View/Edit Human	View/Edit Mouse

F-box only protein 4 is a protein that in humans is encoded by the FBXO4 gene.