FCER1G

FCER1G
Identifiers
Aliases	FCER1G, FCRG, Fc fragment of IgE receptor Ig, Fc epsilon receptor Ig
External IDs	OMIM: 147139; MGI: 95496; HomoloGene: 3029; GeneCards: FCER1G; OMA:FCER1G - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	161,220,699 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	171,061,934 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; right lung; ; upper lobe of left lung; ; blood; ; spleen; ; bone marrow; ; bone marrow cells; ; right coronary artery; ; gallbladder;
	Top expressed in
	granulocyte; ; tibiofemoral joint; ; decidua; ; calvaria; ; stroma of bone marrow; ; blood; ; spleen; ; mesenteric lymph nodes; ; ankle joint; ; dermis;
	More reference expression data
	n/a
Gene ontology
Molecular function	IgE receptor activity; IgG binding; protein binding; IgE binding; transmembrane signaling receptor activity; protein homodimerization activity;
Cellular component	integral component of membrane; membrane; plasma membrane; Fc-epsilon receptor I complex; external side of plasma membrane; tertiary granule membrane; ficolin-1-rich granule membrane; integral component of plasma membrane; cell surface;
Biological process	mast cell activation; positive regulation of phagocytosis; Fc receptor mediated stimulatory signaling pathway; antigen processing and presentation of exogenous peptide antigen via MHC class II; positive regulation of interleukin-10 production; negative regulation of mast cell apoptotic process; receptor internalization; positive regulation of type IIa hypersensitivity; neutrophil activation involved in immune response; serotonin secretion by platelet; stimulatory C-type lectin receptor signaling pathway; blood coagulation; cellular response to low-density lipoprotein particle stimulus; positive regulation of mast cell degranulation; neutrophil chemotaxis; antigen processing and presentation of exogenous peptide antigen via MHC class I; platelet activation; cell surface receptor signaling pathway; phagocytosis, engulfment; positive regulation of immune response; positive regulation of type I hypersensitivity; defense response to bacterium; immunoglobulin mediated immune response; Fc-gamma receptor signaling pathway; positive regulation of mast cell cytokine production; positive regulation of interleukin-6 production; regulation of immune response; positive regulation of tumor necrosis factor production; integrin-mediated signaling pathway; regulation of platelet activation; protein localization to plasma membrane; positive regulation of type III hypersensitivity; T cell differentiation involved in immune response; leukocyte migration; signal transduction; innate immune response; neutrophil degranulation; protein homooligomerization; Fc-epsilon receptor signaling pathway; osteoclast differentiation; interleukin-2 production; positive regulation of protein localization to cell surface; positive regulation of interleukin-4 production; interleukin-3-mediated signaling pathway; immune system process;
	Sources:Amigo / QuickGO
Orthologs
	2207
	14127
	ENSG00000158869
	ENSMUSG00000058715
	P30273
	P20491
	NM_004106
	NM_010185
	NP_004097
	NP_034315
	Wikidata
View/Edit Human	View/Edit Mouse

Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide is gamma chain of high affinity IgE receptor. This protein is encoded by the FCER1G gene in humans.