FCGR1A

FCGR1A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4W4O, 4X4M, 4ZNE
Identifiers
Aliases	FCGR1A, CD64, CD64A, FCRI, IGFR1, Fc fragment of IgG receptor Ia
External IDs	OMIM: 146760; MGI: 95498; HomoloGene: 475; GeneCards: FCGR1A; OMA:FCGR1A - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	149,792,518 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	96,201,285 bp
RNA expression pattern
	Top expressed in
	monocyte; ; granulocyte; ; blood; ; placenta; ; right coronary artery; ; appendix; ; C1 segment; ; substantia nigra; ; testicle; ; bone marrow;
	Top expressed in
	stroma of bone marrow; ; lumbar subsegment of spinal cord; ; calvaria; ; interventricular septum; ; spleen; ; CA3 field; ; embryo; ; granulocyte; ; dermis; ; mesenteric lymph nodes;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; IgG binding;
Cellular component	integral component of membrane; clathrin-coated endocytic vesicle membrane; early endosome membrane; membrane; plasma membrane;
Biological process	immune system process; phagocytosis, engulfment; antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent; immune response; Fc-gamma receptor signaling pathway involved in phagocytosis; signal transduction; regulation of immune response; interferon-gamma-mediated signaling pathway; receptor-mediated endocytosis; innate immune response; positive regulation of protein tyrosine kinase activity;
	Sources:Amigo / QuickGO
Orthologs
	2209
	14129
	ENSG00000150337
	ENSMUSG00000015947
	P12314
	P26151
	NM_000566
	NM_010186
NP_000557; NP_001365733; NP_001365734; NP_001365735; NP_001365736;
	NP_001365737; NP_001365738; NP_001365739; NP_001365740
	NP_034316
	Wikidata
View/Edit Human	View/Edit Mouse

High affinity immunoglobulin gamma Fc receptor I is a protein that in humans is encoded by the FCGR1A gene.