FCRLA

FCRLA
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4HWN
Identifiers
Aliases	FCRLA, FCRL, FCRL1, FCRLM1, FCRLX, FCRLb, FCRLc1, FCRLc2, FCRLd, FCRLe, FCRX, FREB, Fc receptor like A
External IDs	OMIM: 606891; MGI: 2138647; HomoloGene: 13106; GeneCards: FCRLA; OMA:FCRLA - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	161,714,352 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	170,755,152 bp
RNA expression pattern
	Top expressed in
	mucosa of ileum; ; lymph node; ; epithelium of nasopharynx; ; spleen; ; appendix; ; superficial temporal artery; ; pancreatic ductal cell; ; bone marrow cells; ; granulocyte; ; blood;
	Top expressed in
	spleen; ; mesenteric lymph nodes; ; blood; ; granulocyte; ; spermatocyte; ; bone marrow; ; subcutaneous adipose tissue; ; tibiofemoral joint; ; thymus; ; spermatid;
	More reference expression data
	n/a
Orthologs
	84824
	98752
	ENSG00000132185
	ENSMUSG00000038421
	Q7L513
	Q920A9
NM_001184866; NM_001184867; NM_001184870; NM_001184871; NM_001184872;
	NM_001184873; NM_032738; NM_001366195; NM_001366196
	NM_001160215; NM_145141
NP_001171795; NP_001171796; NP_001171799; NP_001171800; NP_001171801;
	NP_001171802; NP_116127; NP_001353124; NP_001353125
	NP_001153687; NP_660123
	Wikidata
View/Edit Human	View/Edit Mouse

Fc receptor-like A is a protein that in humans is encoded by the FCRLA gene.

Receptors for the Fc fragment of IgG, or FCGRs (see MIM 146790), are cell surface glycoproteins of the Ig superfamily (IgSF). These receptors mediate phagocytosis of IgG-coated pathogens and promote activation of effector cells, leading to inflammatory responses and antibody-mediated cellular cytotoxicity. All FCGR genes map to human chromosome 1. Additional genes in this region, including FREB, encode FCGR homologs that are selectively expressed in B cells and may be implicated in B-cell development and lymphomagenesis.[supplied by OMIM]