FDX2

FDX2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2Y5C
Identifiers
Aliases	FDX2, ferredoxin 2, FDX1L, ferredoxin 1 like, MEOAL
External IDs	OMIM: 614585; MGI: 1915415; HomoloGene: 31955; GeneCards: FDX2; OMA:FDX2 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	10,316,015 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	21,073,614 bp
RNA expression pattern
	Top expressed in
	prefrontal cortex; ; anterior cingulate cortex; ; Brodmann area 9; ; right frontal lobe; ; superior frontal gyrus; ; nucleus accumbens; ; Hypothalamus; ; substantia nigra; ; temporal lobe; ; hippocampus proper;
	Top expressed in
	quadriceps femoris muscle; ; white adipose tissue; ; bone marrow; ; muscle of thigh; ; striatum of neuraxis; ; muscle tissue; ; proximal tubule; ; embryo; ; skeletal muscle tissue; ; superior frontal gyrus;
	More reference expression data
	n/a
Gene ontology
Molecular function	iron-sulfur cluster binding; protein binding; metal ion binding; 2 iron, 2 sulfur cluster binding; electron transfer activity;
Cellular component	mitochondrial matrix; mitochondrion;
Biological process	C21-steroid hormone biosynthetic process; sterol metabolic process; small molecule metabolic process; electron transport chain;
	Sources:Amigo / QuickGO
Orthologs
	112812
	68165
	ENSG00000267673
	ENSMUSG00000079677
	Q6P4F2
	Q9CPW2
	NM_080665; NM_001031734; NM_001397406
	NM_001039824
	NP_001026904
	NP_001034913
	Wikidata
View/Edit Human	View/Edit Mouse

Ferredoxin 2 is a protein that in humans is encoded by the FDX2 gene. It participates in heme A synthesis and iron-sulphur protein synthesis.

Mutations in FDX2 cause mitochondrial myopathy.