FERMT1

FERMT1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2KMC, 4BBK
Identifiers
Aliases	FERMT1, C20orf42, DTGCU2, KIND1, UNC112A, URP1, fermitin family member 1, FERM domain containing kindlin 1
External IDs	OMIM: 607900; MGI: 2443583; HomoloGene: 9773; GeneCards: FERMT1; OMA:FERMT1 - orthologs
Gene location (Human)
Chr.	Chromosome 20 (human)
End	6,123,030 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	132,787,826 bp
RNA expression pattern
	Top expressed in
	mucosa of sigmoid colon; ; gingival epithelium; ; hair follicle; ; rectum; ; pancreatic ductal cell; ; skin of thigh; ; mucosa of transverse colon; ; nipple; ; right adrenal cortex; ; human penis;
	Top expressed in
	right kidney; ; colon; ; stomach; ; genital tubercle; ; proximal tubule; ; jejunum; ; ileum; ; duodenum; ; tail of embryo; ; human kidney;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	actin filament binding;
Cellular component	cell projection; ruffle membrane; cytosol; cell junction; filamentous actin; plasma membrane; membrane; focal adhesion; cytoplasm; cytoskeleton;
Biological process	keratinocyte proliferation; cell adhesion; keratinocyte migration; establishment of epithelial cell polarity; positive regulation of cell-matrix adhesion; negative regulation of gene expression; positive regulation of transforming growth factor beta receptor signaling pathway; positive regulation of cell adhesion mediated by integrin; negative regulation of protein import into nucleus; negative regulation of timing of anagen; basement membrane organization; negative regulation of canonical Wnt signaling pathway; negative regulation of stem cell proliferation; integrin-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	55612
	241639
	ENSG00000101311
	ENSMUSG00000027356
	Q9BQL6
	P59113
	NM_017671
	NM_198029
	NP_060141
	NP_932146
	Wikidata
View/Edit Human	View/Edit Mouse

Fermitin family homolog 1 is a protein that in humans is encoded by the FERMT1 gene.