FGD3

FGD3
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2COC
Identifiers
Aliases	FGD3, ZFYVE5, FYVE, RhoGEF and PH domain containing 3
External IDs	OMIM: 617554; MGI: 1353657; HomoloGene: 22925; GeneCards: FGD3; OMA:FGD3 - orthologs
Gene location (Human)
Chr.	Chromosome 9 (human)
End	93,036,236 bp
Gene location (Mouse)
Chr.	Chromosome 13 (mouse)
End	49,473,787 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; blood; ; thymus; ; monocyte; ; spleen; ; bone marrow cells; ; trabecular bone; ; pancreatic ductal cell; ; lymph node; ; appendix;
	Top expressed in
	granulocyte; ; gastrula; ; yolk sac; ; embryo; ; thymus; ; visual cortex; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; primary visual cortex; ; submandibular gland;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion binding; small GTPase binding; guanyl-nucleotide exchange factor activity;
Cellular component	cytoplasm; cytosol; Golgi apparatus; ruffle; cytoskeleton; lamellipodium;
Biological process	regulation of GTPase activity; filopodium assembly; cytoskeleton organization; regulation of cell shape; positive regulation of apoptotic process; regulation of Rho protein signal transduction; regulation of small GTPase mediated signal transduction; actin cytoskeleton organization; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	89846
	30938
	ENSG00000127084
	ENSMUSG00000037946
	Q5JSP0
	O88842
	NM_001083536; NM_001286993; NM_033086; NM_001369951; NM_001369952
	NM_015759
NP_001077005; NP_001273922; NP_149077; NP_001356880; NP_001356881;
	NP_001077005.1; NP_149077.2
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

FYVE, RhoGEF and PH domain-containing protein 3 is a protein that in humans is encoded by the FGD3 gene.