FGF-1 internal ribosome entry site (IRES)

FGF-1 internal ribosome entry site (IRES)
Predicted secondary structure and sequence conservation of IRES_FGF1
Identifiers
SymbolIRES_FGF1
RfamRF00387
Other data
RNA typeCis-reg; IRES
Domain(s)Eukaryota
GOGO:0043022
SOSO:0000243
PDB structuresPDBe

The FGF-1 internal ribosome entry site (IRES) is an RNA element present in the 5' UTR of the mRNA of fibroblast growth factor 1 and allows cap-independent translation. It is thought that FGF-1 internal ribosome entry site (IRES) activity is strictly controlled and highly tissue specific.