FGL2

FGL2
Identifiers
Aliases	FGL2, T49, pT49, fibrinogen like 2
External IDs	OMIM: 605351; MGI: 103266; HomoloGene: 4864; GeneCards: FGL2; OMA:FGL2 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	77,199,848 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	21,583,372 bp
RNA expression pattern
	Top expressed in
	monocyte; ; trigeminal ganglion; ; synovial joint; ; Descending thoracic aorta; ; jejunal mucosa; ; skin of hip; ; spinal ganglia; ; superficial temporal artery; ; urethra; ; human penis;
	Top expressed in
	ascending aorta; ; aortic valve; ; tunica media of zone of aorta; ; uterus; ; ankle; ; granulocyte; ; atrioventricular valve; ; carotid body; ; cervix; ; endothelial cell of lymphatic vessel;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase activity; extracellular matrix structural constituent;
Cellular component	fibrinogen complex; extracellular exosome; extracellular region; ficolin-1-rich granule lumen; collagen-containing extracellular matrix;
Biological process	proteolysis; neutrophil degranulation; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; immunoglobulin production involved in immunoglobulin-mediated immune response; negative regulation of dendritic cell antigen processing and presentation; negative regulation of macrophage antigen processing and presentation; negative regulation of defense response to virus; negative regulation of memory T cell differentiation;
	Sources:Amigo / QuickGO
Orthologs
	10875
	14190
	ENSG00000127951
	ENSMUSG00000039899
	Q14314
	P12804
	NM_006682
	NM_008013
	NP_006673
	NP_032039
	Wikidata
View/Edit Human	View/Edit Mouse

Fibrinogen-like protein 2, also known as FGL2, is a protein which in humans is encoded by the FGL2 gene.