FHL2

FHL2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1X4K, 1X4L, 2D8Z, 2MIU
Identifiers
Aliases	FHL2, AAG11, DRAL, FHL-2, SLIM-3, SLIM3, four and a half LIM domains 2
External IDs	OMIM: 602633; MGI: 1338762; HomoloGene: 20372; GeneCards: FHL2; OMA:FHL2 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	105,438,513 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	43,236,144 bp
RNA expression pattern
	Top expressed in
	myocardium of left ventricle; ; right ventricle; ; apex of heart; ; left ovary; ; right ovary; ; cardiac muscle tissue of right atrium; ; right auricle of heart; ; stromal cell of endometrium; ; urethra; ; saphenous vein;
	Top expressed in
	right ventricle; ; cardiac muscles; ; myocardium of ventricle; ; cardiac muscle tissue of left ventricle; ; interventricular septum; ; atrioventricular valve; ; atrium; ; endocardial cushion; ; stroma of bone marrow; ; mucous cell of stomach;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transcription coactivator activity; transcription factor binding; metal ion binding; protein binding; androgen receptor binding; identical protein binding;
Cellular component	cytoplasm; M band; focal adhesion; nucleoplasm; Z discdkac; nucleus;
Biological process	androgen receptor signaling pathway; regulation of transcription, DNA-templated; heart trabecula formation; regulation of transcription by RNA polymerase II; negative regulation of apoptotic process; negative regulation of transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of transcription, DNA-templated; osteoblast differentiation; response to hormone; atrial cardiac muscle cell development; negative regulation of transcription, DNA-templated; ventricular cardiac muscle cell development; regulation of lipid metabolic process; negative regulation of calcineurin-NFAT signaling cascade;
	Sources:Amigo / QuickGO
Orthologs
	2274
	14200
	ENSG00000115641
	ENSMUSG00000008136
	Q14192
	O70433
NM_001039492; NM_001450; NM_201555; NM_201556; NM_201557;
	NM_001318894; NM_001318895; NM_001318896; NM_001318897; NM_001318898; NM_001318899; NM_001374399
	NM_001289533; NM_010212
NP_001034581; NP_001305823; NP_001305824; NP_001305825; NP_001305826;
	NP_001305827; NP_001305828; NP_001441; NP_963849; NP_963851; NP_001361328
	NP_001276462; NP_034342
	Wikidata
View/Edit Human	View/Edit Mouse

Four and a half LIM domains protein 2 also known as FHL-2 is a protein that in humans is encoded by the FHL2 gene. LIM proteins contain a highly conserved double zinc finger motif called the LIM domain.