Fig4

FIG4
Identifiers
Aliases	FIG4, ALS11, CMT4J, KIAA0274, SAC3, YVS, dJ249I4.1, BTOP, Fig4, FIG4 phosphoinositide 5-phosphatase
External IDs	OMIM: 609390; MGI: 2143585; HomoloGene: 6713; GeneCards: FIG4; OMA:FIG4 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	109,878,098 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	41,179,256 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; endothelial cell; ; lateral nuclear group of thalamus; ; monocyte; ; Brodmann area 23; ; pars compacta; ; pars reticulata; ; parotid gland; ; Achilles tendon; ; nucleus accumbens;
	Top expressed in
	interventricular septum; ; right ventricle; ; epithelium of lens; ; myocardium of ventricle; ; spinal ganglia; ; facial motor nucleus; ; lumbar spinal ganglion; ; atrioventricular valve; ; medial ganglionic eminence; ; atrium;
	More reference expression data
	n/a
Gene ontology
Molecular function	phosphatidylinositol-3-phosphatase activity; phosphatidylinositol-4-phosphate phosphatase activity; phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity; protein binding; phosphatidylinositol bisphosphate phosphatase activity; phosphoric ester hydrolase activity; hydrolase activity;
Cellular component	Golgi membrane; late endosome membrane; endosome; recycling endosome; membrane; endoplasmic reticulum; early endosome membrane; endosome membrane; Golgi apparatus; lipid droplet; intracellular membrane-bounded organelle;
Biological process	locomotory behavior; phosphatidylinositol biosynthetic process; neuron development; phosphatidylinositol metabolic process; positive regulation of neuron projection development; dephosphorylation; pigmentation; myelin assembly; negative regulation of myelination; vacuole organization; phosphatidylinositol-3-phosphate biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	9896
	103199
	ENSG00000112367
	ENSMUSG00000038417
	Q92562
	Q91WF7
	NM_014845
	NM_133999
	NP_055660
	NP_598760
	Wikidata
View/Edit Human	View/Edit Mouse

Polyphosphoinositide phosphatase also known as phosphatidylinositol 3,5-bisphosphate 5-phosphatase or SAC domain-containing protein 3 (Sac3) is an enzyme that in humans is encoded by the FIG4 gene. Fig4 is an abbreviation for Factor-Induced Gene.