FIGLA

FIGLA
Identifiers
Aliases	FIGLA, BHLHC8, FIGALPHA, POF6, folliculogenesis specific bHLH transcription factor
External IDs	OMIM: 608697; MGI: 1349421; HomoloGene: 49294; GeneCards: FIGLA; OMA:FIGLA - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	70,790,643 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	85,997,978 bp
RNA expression pattern
	Top expressed in
	oocyte; ; secondary oocyte; ; testicle; ; gonad; ; body of pancreas; ; gastric mucosa; ; myometrium; ; abdominal wall; ; body of uterus; ; right ovary;
	Top expressed in
	primary oocyte; ; embryo; ; ovarian follicle cell; ; secondary oocyte; ; secondary follicle of ovary; ; zygote; ; lens; ; primary follicle of ovary; ; spermatid; ; spermatocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	RNA polymerase II cis-regulatory region sequence-specific DNA binding; sequence-specific DNA binding; DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; transcription factor binding; protein dimerization activity; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; transcription regulator complex;
Biological process	multicellular organism development; cell differentiation; regulation of transcription, DNA-templated; transcription by RNA polymerase II; transcription, DNA-templated; positive regulation of transcription by RNA polymerase II; oocyte development; oogenesis;
	Sources:Amigo / QuickGO
Orthologs
	344018
	26910
	ENSG00000183733
	ENSMUSG00000030001
	Q6QHK4
	O55208
	NM_001004311
	NM_012013
	NP_001004311
	NP_036143
	Wikidata
View/Edit Human	View/Edit Mouse

Folliculogenesis-specific basic helix-loop-helix, also known as factor in the germline alpha (FIGalpha) or transcription factor FIGa, is a protein that in humans is encoded by the FIGLA gene. The FIGLA gene is a germ cell-specific transcription factor preferentially expressed in oocytes that can be found on human chromosome 2p13.3.