FMNL1

FMNL1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4YDH
Identifiers
Aliases	FMNL1, C17orf1, C17orf1B, FHOD4, FMNL, KW-13, formin like 1
External IDs	OMIM: 604656; MGI: 1888994; HomoloGene: 136798; GeneCards: FMNL1; OMA:FMNL1 - orthologs
Gene location (Human)
Chr.	Chromosome 17 (human)
End	45,247,319 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	103,089,727 bp
RNA expression pattern
	Top expressed in
	granulocyte; ; monocyte; ; blood; ; spleen; ; right lung; ; upper lobe of left lung; ; lymph node; ; bone marrow cells; ; appendix; ; gallbladder;
	Top expressed in
	granulocyte; ; primary visual cortex; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; perirhinal cortex; ; tibiofemoral joint; ; thymus; ; entorhinal cortex; ; lumbar spinal ganglion; ; interventricular septum;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	profilin binding; GTPase activating protein binding; actin filament binding; protein binding; actin binding; molecular function;
Cellular component	cytoplasm; cell projection; membrane; plasma membrane; cell cortex; phagocytic vesicle; bleb; extracellular exosome; cytoplasmic vesicle; cytosol; integral component of membrane;
Biological process	actin filament severing; substrate-dependent cell migration; cytoskeleton organization; regulation of cell shape; cellular component organization; cortical actin cytoskeleton organization; actin cytoskeleton organization; cellular process or phenomenon;
	Sources:Amigo / QuickGO
Orthologs
	752
	57778
	ENSG00000184922
	ENSMUSG00000055805
	O95466
	Q9JL26
	NM_005892
	NM_001077698; NM_019679
	NP_005883
NP_001071166; NP_062653; NP_001390541; NP_001390542; NP_001390543;
	NP_001390544; NP_001390545; NP_001390546; NP_001390547
	Wikidata
View/Edit Human	View/Edit Mouse

Formin-like protein 1 is a protein that in humans is encoded by the FMNL1 gene.

This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. An alternative splice variant has been described but its full length sequence has not been determined.