FOXL2

FOXL2
Identifiers
Aliases	FOXL2, BPES, BPES1, PFRK, PINTO, POF3, forkhead box L2
External IDs	OMIM: 605597; MGI: 1349428; HomoloGene: 74992; GeneCards: FOXL2; OMA:FOXL2 - orthologs
Gene location (Human)
Chr.	Chromosome 3 (human)
End	138,947,137 bp
Gene location (Mouse)
Chr.	Chromosome 9 (mouse)
End	98,840,596 bp
RNA expression pattern
	Top expressed in
	left ovary; ; stromal cell of endometrium; ; right ovary; ; gonad; ; canal of the cervix; ; decidua; ; testicle; ; left uterine tube; ; pituitary gland; ; right uterine tube;
	Top expressed in
	membrana granulosa of ovarian follicle; ; cumulus cell; ; ovarian follicle cell; ; Stroma of ovary; ; gastrula; ; eyelid; ; urethra; ; male urethra; ; cervix; ; Cumulus oophorus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	DNA binding; sequence-specific DNA binding; DNA-binding transcription factor activity; DNA-binding transcription activator activity, RNA polymerase II-specific; cysteine-type endopeptidase regulator activity involved in apoptotic process; RNA polymerase II cis-regulatory region sequence-specific DNA binding; protein binding; estrogen receptor binding; ubiquitin conjugating enzyme binding; DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	nucleus; intercellular bridge; nucleoplasm;
Biological process	oocyte growth; apoptotic DNA fragmentation; regulation of transcription, DNA-templated; extraocular skeletal muscle development; embryonic eye morphogenesis; positive regulation of follicle-stimulating hormone secretion; negative regulation of transcription by RNA polymerase II; transcription by RNA polymerase II; transcription, DNA-templated; female gonad development; single fertilization; uterus development; positive regulation of transcription, DNA-templated; positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; positive regulation of apoptotic process; ovarian follicle development; negative regulation of transcription, DNA-templated; female somatic sex determination; granulosa cell differentiation; positive regulation of luteinizing hormone secretion; positive regulation of transcription by RNA polymerase II; anatomical structure morphogenesis; cell differentiation; regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	668
	26927
	ENSG00000183770
	ENSMUSG00000050397
	P58012
	O88470
	NM_023067
	NM_012020
	NP_075555
	NP_036150
	Wikidata
View/Edit Human	View/Edit Mouse

Forkhead box protein L2 is a protein that in humans is encoded by the FOXL2 gene.