FSCN1

FSCN1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1DFC, 4GP0, 4GP3, 3P53, 4GOY, 4GOV, 3LLP
Identifiers
Aliases	FSCN1, FAN1, HSN, SNL, p55, fascin actin-bundling protein 1
External IDs	OMIM: 602689; MGI: 1352745; HomoloGene: 48164; GeneCards: FSCN1; OMA:FSCN1 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	5,606,655 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	142,958,940 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; ganglionic eminence; ; middle frontal gyrus; ; frontal pole; ; Brodmann area 10; ; C1 segment; ; ventricular zone; ; right frontal lobe; ; putamen; ; Amygdala;
	Top expressed in
	external carotid artery; ; internal carotid artery; ; abdominal wall; ; Rostral migratory stream; ; endothelial cell of lymphatic vessel; ; condyle; ; primitive streak; ; endocardial cushion; ; fossa; ; mandibular prominence;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	protein-macromolecule adaptor activity; actin filament binding; protein binding; actin binding; RNA binding; cadherin binding;
Cellular component	cytoplasm; cell projection; cell-cell junction; filopodium; ruffle; myelin sheath; stress fiber; microvillus; cell junction; microspike; cell projection membrane; actin cytoskeleton; podosome; extracellular exosome; cytoskeleton; growth cone; lamellipodium; filamentous actin; cytosol;
Biological process	regulation of microvillus assembly; establishment of apical/basal cell polarity; regulation of actin cytoskeleton organization; actin filament organization; cell motility; positive regulation of podosome assembly; actin filament bundle assembly; positive regulation of extracellular matrix disassembly; cell-cell junction assembly; microspike assembly; cell population proliferation; positive regulation of lamellipodium assembly; cell migration; positive regulation of filopodium assembly; actin cytoskeleton organization; anatomical structure morphogenesis; establishment or maintenance of cell polarity; cytokine-mediated signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	6624
	14086
	ENSG00000075618
	ENSMUSG00000029581
	Q16658
	Q61553
	NM_003088
	NM_007984
	NP_003079
	NP_032010
	Wikidata
View/Edit Human	View/Edit Mouse

Fascin is a protein that in humans is encoded by the FSCN1 gene.