FTSJ1

FTSJ1
Identifiers
Aliases	FTSJ1, CDLIV, MRX44, MRX9, SPB1, TRMT7, JM23, FtsJ RNA methyltransferase homolog 1 (E. coli), FtsJ RNA methyltransferase homolog 1, FtsJ RNA 2'-O-methyltransferase 1, XLID9
External IDs	OMIM: 300499; MGI: 1859648; HomoloGene: 5372; GeneCards: FTSJ1; OMA:FTSJ1 - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	48,486,364 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	8,118,645 bp
RNA expression pattern
	Top expressed in
	stromal cell of endometrium; ; granulocyte; ; body of pancreas; ; ganglionic eminence; ; left uterine tube; ; cerebellar hemisphere; ; right hemisphere of cerebellum; ; right lobe of thyroid gland; ; ascending aorta; ; left adrenal cortex;
	Top expressed in
	genital tubercle; ; external carotid artery; ; internal carotid artery; ; fetal liver hematopoietic progenitor cell; ; crypt of lieberkuhn of small intestine; ; tail of embryo; ; medial ganglionic eminence; ; hair follicle; ; barrel cortex; ; left lobe of liver;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; tRNA (guanosine-2'-O-)-methyltransferase activity; tRNA (cytosine-2'-O-)-methyltransferase activity; tRNA methyltransferase activity;
Cellular component	cytosol; cytoplasm;
Biological process	methylation; RNA methylation; tRNA processing; tRNA modification; cytoplasmic translation; tRNA methylation; tRNA nucleoside ribose methylation;
	Sources:Amigo / QuickGO
Orthologs
	24140
	54632
	ENSG00000068438
	ENSMUSG00000031171
	Q9UET6
	n/a
	NM_001282157; NM_012280; NM_177439
	NM_001290430; NM_133991
	NP_001269086; NP_036412; NP_803188
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Putative ribosomal RNA methyltransferase 1 is an enzyme that in humans is encoded by the FTSJ1 gene.

The protein encoded by this gene is a member of the S-adenosylmethionine-binding protein family. It is a nucleolar protein and may be involved in the processing and modification of rRNA. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.