FUT9

FUT9
Identifiers
Aliases	FUT9, Fuc-TIX, fucosyltransferase 9
External IDs	OMIM: 606865; MGI: 1330859; HomoloGene: 4800; GeneCards: FUT9; OMA:FUT9 - orthologs
Gene location (Human)
Chr.	Chromosome 6 (human)
End	96,215,612 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	25,800,244 bp
RNA expression pattern
	Top expressed in
	pylorus; ; cerebellar vermis; ; Brodmann area 46; ; endothelial cell; ; orbitofrontal cortex; ; postcentral gyrus; ; Brodmann area 23; ; middle temporal gyrus; ; entorhinal cortex; ; pars reticulata;
	Top expressed in
	lobe of cerebellum; ; cerebellar vermis; ; lateral geniculate nucleus; ; medial geniculate nucleus; ; dorsal tegmental nucleus; ; medial dorsal nucleus; ; lateral hypothalamus; ; medial vestibular nucleus; ; deep cerebellar nuclei; ; globus pallidus;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	glycosyltransferase activity; alpha-(1->3)-fucosyltransferase activity; fucosyltransferase activity; transferase activity;
Cellular component	integral component of membrane; Golgi apparatus; Golgi cisterna membrane; membrane; Golgi membrane;
Biological process	L-fucose catabolic process; fucosylation; nervous system development; protein glycosylation; carbohydrate metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	10690
	14348
	ENSG00000172461
	ENSMUSG00000055373
	Q9Y231
	O88819
	NM_006581
	NM_010243
	NP_006572
	NP_034373
	Wikidata
View/Edit Human	View/Edit Mouse

Alpha-(1,3)-fucosyltransferase is an enzyme that in humans is encoded by the FUT9 gene.

FUT9 is one of several alpha-3-fucosyltransferases that can catalyze the last step in the biosynthesis of Lewis antigen, the addition of a fucose to precursor polysaccharides. FUT9 synthesizes the LeX oligosaccharide (CD15), which is expressed in organ buds progressing in mesenchyma during human embryogenesis.[supplied by OMIM]