FZR1

FZR1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4UI9
Identifiers
Aliases	FZR1, CDC20C, CDH1, FZR, FZR2, HCDH, HCDH1, fizzy/cell division cycle 20 related 1, fizzy and cell division cycle 20 related 1
External IDs	OMIM: 603619; MGI: 1926790; HomoloGene: 9444; GeneCards: FZR1; OMA:FZR1 - orthologs
Gene location (Human)
Chr.	Chromosome 19 (human)
End	3,538,334 bp
Gene location (Mouse)
Chr.	Chromosome 10 (mouse)
End	81,214,350 bp
RNA expression pattern
	Top expressed in
	ventricular zone; ; left testis; ; right testis; ; sural nerve; ; anterior pituitary; ; ganglionic eminence; ; skin of leg; ; right hemisphere of cerebellum; ; tendon of biceps brachii; ; stromal cell of endometrium;
	Top expressed in
	spermatid; ; seminiferous tubule; ; ventricular zone; ; spermatocyte; ; interventricular septum; ; yolk sac; ; fetal liver hematopoietic progenitor cell; ; dentate gyrus of hippocampal formation granule cell; ; neural tube; ; primary visual cortex;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein binding; anaphase-promoting complex binding; ubiquitin-protein transferase activator activity;
Cellular component	cytoplasm; cytosol; nuclear membrane; nucleoplasm; anaphase-promoting complex; nucleus;
Biological process	positive regulation of protein catabolic process; regulation of meiotic nuclear division; cellular response to DNA damage stimulus; cell division; protein K11-linked ubiquitination; lens fiber cell differentiation; protein ubiquitination; positive regulation of cell population proliferation; cell cycle; anaphase-promoting complex-dependent catabolic process; DNA repair; positive regulation of ubiquitin protein ligase activity; mitotic G2 DNA damage checkpoint signaling; regulation of mitotic cell cycle phase transition; ubiquitin-dependent protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	51343
	56371
	ENSG00000105325
	ENSMUSG00000020235
	Q9UM11
	Q9R1K5
	NM_001136197; NM_001136198; NM_016263
	NM_019757
	NP_001129669; NP_001129670; NP_057347
	NP_062731
	Wikidata
View/Edit Human	View/Edit Mouse

Fizzy-related protein homolog, also known as hCDH1, is a protein that in humans is encoded by the FZR1 gene.