TNF receptor associated periodic syndrome
| TNF receptor associated periodic syndrome | |
|---|---|
| Other names | Familial Hibernian fever, Tumor necrosis factor receptor associated periodic syndrome |
| Specialty | Immunology |
| Symptoms | Vertigo, pericarditis |
| Causes | Mutations in the TNFRSF1A gene |
| Diagnostic method | Blood test, Genetic test |
| Treatment | Corticosteroids, NSAIDS |
TNF receptor associated periodic syndrome (TRAPS) is a periodic fever syndrome associated with mutations in a receptor for the molecule tumor necrosis factor (TNF) that is inheritable in an autosomal dominant manner. Individuals with TRAPS have episodic symptoms such as recurrent high fevers, rash, abdominal pain, joint/muscle aches and puffy eyes.