TNF receptor associated periodic syndrome

TNF receptor associated periodic syndrome
Other namesFamilial Hibernian fever, Tumor necrosis factor receptor associated periodic syndrome
SpecialtyImmunology
SymptomsVertigo, pericarditis
CausesMutations in the TNFRSF1A gene
Diagnostic methodBlood test, Genetic test
TreatmentCorticosteroids, NSAIDS

TNF receptor associated periodic syndrome (TRAPS) is a periodic fever syndrome associated with mutations in a receptor for the molecule tumor necrosis factor (TNF) that is inheritable in an autosomal dominant manner. Individuals with TRAPS have episodic symptoms such as recurrent high fevers, rash, abdominal pain, joint/muscle aches and puffy eyes.