Fatty-acid amide hydrolase 1

FAAH
Identifiers
Aliases	FAAH, fatty acid amide hydrolase, FAAH-1, PSAB
External IDs	OMIM: 602935; MGI: 109609; HomoloGene: 68184; GeneCards: FAAH; OMA:FAAH - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	46,413,848 bp
Gene location (Mouse)
Chr.	Chromosome 4 (mouse)
End	115,875,123 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; left lobe of thyroid gland; ; mucosa of transverse colon; ; C1 segment; ; right hemisphere of cerebellum; ; left testis; ; right testis; ; right lobe of liver; ; nucleus accumbens; ; body of pancreas;
	Top expressed in
	dentate gyrus of hippocampal formation granule cell; ; left lobe of liver; ; primary visual cortex; ; CA3 field; ; perirhinal cortex; ; superior frontal gyrus; ; entorhinal cortex; ; right kidney; ; gallbladder; ; hippocampus proper;
	More reference expression data
	n/a
Gene ontology
Molecular function	protein binding; hydrolase activity; acylglycerol lipase activity; fatty acid amide hydrolase activity; amidase activity;
Cellular component	cytoplasm; organelle membrane; integral component of membrane; cytoskeleton; endoplasmic reticulum membrane; endomembrane system; membrane;
Biological process	arachidonic acid metabolic process; fatty acid catabolic process; monoacylglycerol catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	2166
	14073
	ENSG00000117480
	ENSMUSG00000034171
	O00519
	O08914
	NM_001441
	NM_010173
	NP_001432
	NP_034303
	Wikidata
View/Edit Human	View/Edit Mouse

Fatty-acid amide hydrolase 1 (FAAH) is a member of the serine hydrolase family of enzymes. It was first shown to break down anandamide (AEA), an N-acylethanolamine (NAE) in 1993. In humans, it is encoded by the gene FAAH.