Fibrous cap

The fibrous cap is a layer of fibrous connective tissue, which is thicker and less cellular than the normal intima, found in atheromatous plaques. The fibrous cap contains macrophages and smooth muscle cells. The fibrous cap of an atheroma is composed of bundles of muscle cells, macrophages, foam cells, lymphocytes, collagen and elastin. An atheroma with a cap is termed a fibrous cap atheroma.