FBLN1

FBLN1
Identifiers
Aliases	FBLN1, FBLN, FIBL1, fibulin 1
External IDs	OMIM: 135820; MGI: 95487; HomoloGene: 21295; GeneCards: FBLN1; OMA:FBLN1 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	45,601,135 bp
Gene location (Mouse)
Chr.	Chromosome 15 (mouse)
End	85,170,736 bp
RNA expression pattern
	Top expressed in
	canal of the cervix; ; gallbladder; ; vena cava; ; pericardium; ; gastric mucosa; ; ectocervix; ; vagina; ; left uterine tube; ; right auricle of heart; ; tendon of biceps brachii;
	Top expressed in
	aortic valve; ; otic vesicle; ; ascending aorta; ; otic placode; ; ciliary body; ; external carotid artery; ; saccule; ; mandibular prominence; ; internal carotid artery; ; maxillary prominence;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	fibronectin binding; calcium ion binding; extracellular matrix structural constituent; fibrinogen binding; integrin binding; protein C-terminus binding; protein binding; identical protein binding; peptidase activator activity; protein-containing complex binding;
Cellular component	elastic fiber; extracellular matrix; fibrinogen complex; basement membrane; extracellular exosome; extracellular space; extracellular region; collagen-containing extracellular matrix;
Biological process	negative regulation of protein phosphorylation; negative regulation of cell adhesion; negative regulation of stem cell proliferation; positive regulation of fibroblast proliferation; positive regulation of substrate-dependent cell migration, cell attachment to substrate; negative regulation of cell motility; negative regulation of transformation of host cell by virus; positive regulation of peptidase activity; positive regulation of gene expression; negative regulation of ERK1 and ERK2 cascade; integrin-mediated signaling pathway; blood coagulation, fibrin clot formation; negative regulation of substrate adhesion-dependent cell spreading; viral process; embryo implantation; extracellular matrix organization;
	Sources:Amigo / QuickGO
Orthologs
	2192
	14114
	ENSG00000077942
	ENSMUSG00000006369
	P23142
	Q08879
	NM_006487; NM_001996; NM_006485; NM_006486
	NM_010180; NM_001347088
	NP_001987; NP_006476; NP_006477; NP_006478
	NP_001334017; NP_034310
	Wikidata
View/Edit Human	View/Edit Mouse

FBLN1 is the gene encoding fibulin-1, an extracellular matrix and plasma protein.