Formiminoglutamic acid

Formiminoglutamic acid
Names
IUPAC name
N-(aminomethylidene)-L-glutamic acid
Other names
FIGLU
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.011.308
MeSH Formiminoglutamic+acid
UNII
  • C(CC(=O)O)C(C(=O)O)N=CN
Properties
C6H10N2O4
Molar mass 174.156 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Formiminoglutamic acid (FIGLU; conjugate base, formiminoglutamate) is an intermediate in the catabolism of L-histidine to L-glutamic acid. It thus is also a biomarker for intracellular levels of folate. The FIGLU test is used to identify vitamin B₁₂ deficiency, folate deficiency, and liver failure or liver disease. It is elevated with folate trapping, where it is accompanied by decreased methylmalonic acid, increased folate and a decrease in homocysteine.