Forskolin

Forskolin
Names
	IUPAC name (13R)-1α,6β,9α-Trihydroxy-11-oxo-8α,13-epoxylabd-14-en-7β-yl acetate
	Systematic IUPAC name (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-3-Ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-naphtho[2,1-b]pyran-5-yl acetate
Identifiers
CAS Number	66575-29-9 ;
3D model (JSmol)	Interactive image;
ChEBI	CHEBI:42471 ;
ChEMBL	ChEMBL52606 ;
ChemSpider	43607 ;
DrugBank	DB02587 ;
ECHA InfoCard	100.060.354
IUPHAR/BPS	5190;
PubChem CID	47936;
UNII	1F7A44V6OU ;
CompTox Dashboard (EPA)	DTXSID8040484 ;
	InChI InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1 Key: OHCQJHSOBUTRHG-KGGHGJDLSA-N ; InChI=1/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1 Key: OHCQJHSOBUTRHG-KGGHGJDLBB;
	SMILES CC(=O)O[C@H]1[C@H]([C@@H]2[C@]([C@H](CCC2(C)C)O)([C@@]3([C@@]1(O[C@@](CC3=O)(C)C=C)C)O)C)O;
Properties
Chemical formula	C22H34O7
Molar mass	410.507 g·mol−1
Solubility	Soluble in organic solvents such as ethanol, chloroform and DMSO
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). verify (what is ?) Infobox references

Forskolin (coleonol) is a labdane diterpene produced by the plant Coleus barbatus (blue spur flower). Other names include pashanabhedi, Indian coleus, makandi, HL-362, mao hou qiao rui hua. As with other members of the large diterpene class of plant metabolites, forskolin is derived from geranylgeranyl pyrophosphate (GGPP). Forskolin contains some unique functional elements, including the presence of a tetrahydropyran-derived heterocyclic ring.

Forskolin is commonly used in laboratory research to increase levels of cyclic AMP by stimulation of adenylate cyclase.