Fructosephosphates

Fructose phosphates are sugar phosphates based upon fructose, and are common in the biochemistry of cells. A fructose phosphate is formed when fructose is phosphorylated through the addition of an inorganic phosphate group (Pi).

Fructose is a naturally occurring monosaccharide and is referred to as a “fruit sugar” due to existing in virtually every fruit. Fructose is a six-carbon molecule and can be drawn as a linear chain (Fischer Projection) or a ring-like structure (Haworth Projection), consisting of carbon and hydroxyl groups. Inorganic phosphate is an anion that plays a fundamental role in various key biological processes.

Fructose phosphates play integral roles in many metabolic pathways, particularly glycolysis, gluconeogenesis, oxidative phosphorylation, and lipogenesis. Furthermore, biomedical research has increasingly demonstrated the role of fructose phosphates in metabolic processes and how dysregulation of their production or metabolism can contribute to several human diseases.

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