G3BP2

G3BP2
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	5DRV
Identifiers
Aliases	G3BP2, G3BP stress granule assembly factor 2
External IDs	MGI: 2442040; HomoloGene: 137244; GeneCards: G3BP2; OMA:G3BP2 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	75,724,589 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	92,231,578 bp
RNA expression pattern
	Top expressed in
	internal globus pallidus; ; islet of Langerhans; ; Achilles tendon; ; frontal pole; ; Pons; ; pars compacta; ; lateral nuclear group of thalamus; ; Skeletal muscle tissue of rectus abdominis; ; germinal epithelium; ; epithelium of colon;
	Top expressed in
	zygote; ; secondary oocyte; ; tail of embryo; ; blood; ; anterior horn of spinal cord; ; genital tubercle; ; nucleus accumbens; ; primary oocyte; ; abdominal wall; ; facial motor nucleus;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	signaling receptor complex adaptor activity; protein binding; nucleic acid binding; mRNA binding; RNA binding;
Cellular component	intracellular anatomical structure; cytoplasm; cytosol; ribonucleoprotein complex; cytoplasmic stress granule;
Biological process	mRNA transport; Ras protein signal transduction; cytoplasmic sequestering of NF-kappaB; stress granule assembly; transport; positive regulation of signal transduction; viral process; protein homooligomerization; positive regulation of stress granule assembly; immune system process; innate immune response;
	Sources:Amigo / QuickGO
Orthologs
	9908
	23881
	ENSG00000138757
	ENSMUSG00000029405
	Q9UN86
	P97379
	NM_012297; NM_203504; NM_203505
NM_001080794; NM_001080795; NM_001080796; NM_001080797; NM_011816;
	NM_001359195; NM_001359196; NM_001359197
	NP_036429; NP_987100; NP_987101; NP_987100.1
NP_001074263; NP_001074264; NP_001074265; NP_001074266; NP_035946;
	NP_001346124; NP_001346125; NP_001346126
	Wikidata
View/Edit Human	View/Edit Mouse

Ras GTPase-activating protein-binding protein 2 is an enzyme that in humans is encoded by the G3BP2 gene.