GABPB2

GABPB1
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1AWC
Identifiers
Aliases	GABPB1, BABPB2, E4TF1, E4TF1-47, E4TF1-53, E4TF1B, GABPB, GABPB2, NRF2B1, NRF2B2, GABPB-1, GA binding protein transcription factor beta subunit 1, GA binding protein transcription factor subunit beta 1
External IDs	OMIM: 600610; MGI: 95611; HomoloGene: 7723; GeneCards: GABPB1; OMA:GABPB1 - orthologs
Gene location (Human)
Chr.	Chromosome 15 (human)
End	50,355,408 bp
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	126,518,257 bp
RNA expression pattern
	Top expressed in
	secondary oocyte; ; cartilage tissue; ; bone marrow cells; ; ventricular zone; ; ganglionic eminence; ; Achilles tendon; ; stromal cell of endometrium; ; testicle; ; gonad; ; lactiferous duct;
	Top expressed in
	tail of embryo; ; ventricular zone; ; granulocyte; ; genital tubercle; ; thymus; ; ganglionic eminence; ; epiblast; ; spermatid; ; embryo; ; primary oocyte;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; protein heterodimerization activity; protein binding;
Cellular component	nucleus; nucleoplasm; cytoplasmic ribonucleoprotein granule;
Biological process	regulation of transcription, DNA-templated; mitochondrion organization; positive regulation of transcription by RNA polymerase II; regulation of transcription by RNA polymerase II; transcription, DNA-templated;
	Sources:Amigo / QuickGO
Orthologs
	2553
	14391
	ENSG00000104064
	ENSMUSG00000027361
	Q06547
	Q00420
NM_002041; NM_005254; NM_016654; NM_016655; NM_181427;
	NM_001320910; NM_001320915
NM_001271467; NM_001271468; NM_001271469; NM_001271470; NM_001271492;
	NM_010249; NM_207669; NM_001355108; NM_001355109
NP_001307839; NP_001307844; NP_002032; NP_005245; NP_057738;
	NP_057739; NP_852092; NP_057738.1
NP_001258396; NP_001258397; NP_001258398; NP_001258399; NP_001258421;
	NP_034379; NP_997552; NP_001342037; NP_001342038; NP_001393121; NP_001393122; NP_001393123; NP_001393124; NP_001393125; NP_001393126; NP_001393127; NP_001393128; NP_001393129; NP_001393130; NP_001393131; NP_001393132; NP_001393133; NP_001393134; NP_001393135; NP_001393136; NP_001393137; NP_001393138; NP_001393139; NP_001393140; NP_001393141; NP_001393142; NP_001393143; NP_001393144; NP_001393145; NP_001393146; NP_001393147; NP_001393148; NP_001393149; NP_001393150; NP_001393151; NP_001393152; NP_001393153; NP_001393154; NP_001393155; NP_001393156
	Wikidata
View/Edit Human	View/Edit Mouse

GA-binding protein subunit beta-1 is a protein that in humans is encoded by the GABPB1 gene.

This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.