Gamma-aminobutyric acid receptor subunit gamma-2

GABRG2
Identifiers
Aliases	GABRG2, CAE2, ECA2, GEFSP3, gamma-aminobutyric acid type A receptor gamma2 subunit, EIEE74, FEB8
External IDs	OMIM: 137164; MGI: 95623; HomoloGene: 22443; GeneCards: GABRG2; OMA:GABRG2 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	162,162,977 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	41,891,684 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; Brodmann area 23; ; superior frontal gyrus; ; primary visual cortex; ; postcentral gyrus; ; frontal pole; ; Pons; ; prefrontal cortex; ; endothelial cell; ; entorhinal cortex;
	Top expressed in
	visual cortex; ; primary visual cortex; ; superior frontal gyrus; ; perirhinal cortex; ; central gray substance of midbrain; ; entorhinal cortex; ; dentate gyrus of hippocampal formation granule cell; ; cerebellar cortex; ; lateral hypothalamus; ; ventral tegmental area;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	protein binding; benzodiazepine receptor activity; extracellular ligand-gated ion channel activity; chloride channel activity; GABA-A receptor activity; ion channel activity; transmembrane signaling receptor activity; inhibitory extracellular ligand-gated ion channel activity; GABA-gated chloride ion channel activity; transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential;
Cellular component	integral component of membrane; postsynaptic membrane; membrane; synapse; dendrite membrane; chloride channel complex; axon; cell junction; integral component of plasma membrane; plasma membrane; dendrite; cytoplasmic vesicle membrane; cytoplasmic vesicle; cell projection; GABA-A receptor complex; neuron projection; postsynapse; GABA-ergic synapse;
Biological process	gamma-aminobutyric acid signaling pathway; synaptic transmission, GABAergic; ion transport; post-embryonic development; adult behavior; chloride transport; cellular response to histamine; chemical synaptic transmission; chloride transmembrane transport; ion transmembrane transport; signal transduction; regulation of membrane potential; nervous system process; regulation of postsynaptic membrane potential; inhibitory synapse assembly;
	Sources:Amigo / QuickGO
Orthologs
	2566
	14406
	ENSG00000113327
	ENSMUSG00000020436
	P18507
	P22723
	NM_198904; NM_000816; NM_198903
	NM_008073; NM_177408; NM_001362655; NM_001362656
NP_000807; NP_944493; NP_944494; NP_001362268; NP_001362269;
	NP_001362270; NP_001362271; NP_001362272; NP_001362273; NP_001362274; NP_001362275; NP_001362276; NP_001362277; NP_001362278; NP_001362279
	NP_032099; NP_803127; NP_001349584; NP_001349585
	Wikidata
View/Edit Human	View/Edit Mouse

Gamma-aminobutyric acid receptor subunit gamma-2 is a protein that in humans is encoded by the GABRG2 gene.