GABRQ

GABRQ
Identifiers
Aliases	GABRQ, THETA, gamma-aminobutyric acid type A receptor theta subunit, gamma-aminobutyric acid type A receptor subunit theta
External IDs	OMIM: 300349; MGI: 1888498; HomoloGene: 10233; GeneCards: GABRQ; OMA:GABRQ - orthologs
Gene location (Human)
Chr.	X chromosome (human)
End	152,657,542 bp
Gene location (Mouse)
Chr.	X chromosome (mouse)
End	71,886,208 bp
RNA expression pattern
	Top expressed in
	Hypothalamus; ; gonad; ; tibialis anterior muscle; ; anterior cingulate cortex; ; Amygdala; ; hippocampus proper; ; superior vestibular nucleus; ; ectocervix; ; canal of the cervix; ; prefrontal cortex;
	Top expressed in
	secondary oocyte; ; zygote; ; ventromedial nucleus; ; dorsomedial hypothalamic nucleus; ; arcuate nucleus; ; superior frontal gyrus; ; lateral hypothalamus; ; cerebellar cortex; ; median eminence; ; supraoptic nucleus;
	More reference expression data
	n/a
Gene ontology
Molecular function	GABA-A receptor activity; neurotransmitter transmembrane transporter activity; chloride channel activity; extracellular ligand-gated ion channel activity; ion channel activity; transmembrane signaling receptor activity;
Cellular component	integral component of membrane; GABA-A receptor complex; postsynaptic membrane; membrane; receptor complex; plasma membrane; synapse; integral component of plasma membrane; chloride channel complex; cell junction; neuron projection;
Biological process	chloride transmembrane transport; ion transport; chloride transport; signal transduction; neurotransmitter transport; ion transmembrane transport; chemical synaptic transmission; regulation of membrane potential; nervous system process;
	Sources:Amigo / QuickGO
Orthologs
	55879
	57249
	ENSG00000268089
	ENSMUSG00000031344
	Q9UN88
	Q9JLF1
	NM_018558
	NM_001290435; NM_020488
	NP_061028
	NP_001277364; NP_065234
	Wikidata
View/Edit Human	View/Edit Mouse

Gamma-aminobutyric acid receptor subunit theta is a protein that in humans is encoded by the GABRQ gene. The protein encoded by this gene is a subunit of the GABAA receptor.

The θ subunit has highest sequence similarity with the β1 subunit. This subunit coassembles with:

α2, β1, and γ1
α3 and β1
α3, β1, and ε.