GAK (protein)

GAK
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	4C57, 4C58, 4C59, 4O38, 4Y8D
Identifiers
Aliases	GAK, D130045N16Rik, DNAJ26, DNAJC26, cyclin G associated kinase
External IDs	OMIM: 602052; MGI: 2442153; HomoloGene: 3846; GeneCards: GAK; OMA:GAK - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	932,373 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	108,777,621 bp
RNA expression pattern
	Top expressed in
	pancreatic ductal cell; ; endothelial cell; ; mucosa of transverse colon; ; granulocyte; ; right hemisphere of cerebellum; ; minor salivary glands; ; mucosa of ileum; ; left testis; ; body of stomach; ; right testis;
	Top expressed in
	tail of embryo; ; genital tubercle; ; granulocyte; ; intestinal villus; ; dentate gyrus of hippocampal formation granule cell; ; crypt of lieberkuhn of small intestine; ; duodenum; ; epithelium of small intestine; ; thymus; ; lip;
	More reference expression data
	n/a
Gene ontology
Molecular function	transferase activity; nucleotide binding; protein serine/threonine kinase activity; protein kinase activity; protein binding; ATP binding; kinase activity; cyclin binding; chaperone binding; clathrin binding;
Cellular component	cytoplasm; perinuclear region of cytoplasm; vesicle; cell junction; Golgi apparatus; membrane; intracellular membrane-bounded organelle; focal adhesion; cytosol; synapse; presynapse;
Biological process	protein phosphorylation; cell cycle; negative regulation of neuron projection development; Golgi organization; phosphorylation; clathrin-dependent endocytosis; clathrin coat disassembly; Golgi to lysosome transport; endoplasmic reticulum organization; synaptic vesicle uncoating; chaperone cofactor-dependent protein refolding; membrane organization; clathrin-coated pit assembly; receptor-mediated endocytosis; protein localization to plasma membrane; protein localization to Golgi apparatus;
	Sources:Amigo / QuickGO
Orthologs
	2580
	231580
	ENSG00000178950
	ENSMUSG00000062234
	O14976
	Q99KY4
	NM_001286833; NM_005255; NM_001318134
NM_001282051; NM_001282052; NM_153569; NM_001359922; NM_001359923;
	NM_001359924
	NP_001305063; NP_005246
NP_001268980; NP_001268981; NP_705797; NP_001346851; NP_001346852;
	NP_001346853
	Wikidata
View/Edit Human	View/Edit Mouse

Cyclin G-associated kinase (GAK) is a serine/threonine kinase that in humans is encoded by the GAK gene.