GAL3ST1

GAL3ST1
Identifiers
Aliases	GAL3ST1, CST, galactose-3-O-sulfotransferase 1
External IDs	OMIM: 602300; MGI: 1858277; HomoloGene: 3574; GeneCards: GAL3ST1; OMA:GAL3ST1 - orthologs
Gene location (Human)
Chr.	Chromosome 22 (human)
End	30,574,665 bp
Gene location (Mouse)
Chr.	Chromosome 11 (mouse)
End	3,949,326 bp
RNA expression pattern
	Top expressed in
	C1 segment; ; tibial nerve; ; gonad; ; putamen; ; duodenum; ; nucleus accumbens; ; Amygdala; ; caudate nucleus; ; substantia nigra; ; sural nerve;
	Top expressed in
	pyloric antrum; ; epithelium of stomach; ; mucous cell of stomach; ; right kidney; ; duodenum; ; lumbar subsegment of spinal cord; ; anterior horn of spinal cord; ; deep cerebellar nuclei; ; sciatic nerve; ; optic nerve;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	transferase activity; sulfotransferase activity; galactosylceramide sulfotransferase activity;
Cellular component	integral component of membrane; Golgi membrane; Golgi apparatus; integral component of plasma membrane; membrane;
Biological process	glycolipid biosynthetic process; myelination; galactosylceramide biosynthetic process; protein N-linked glycosylation; spermatogenesis; sphingolipid metabolic process; lipid metabolism;
	Sources:Amigo / QuickGO
Orthologs
	9514
	53897
	ENSG00000128242
	ENSMUSG00000049721
	Q99999
	Q9JHE4
NM_004861; NM_001318103; NM_001318104; NM_001318105; NM_001318106;
	NM_001318107; NM_001318108; NM_001318109; NM_001318110; NM_001318111; NM_001318112; NM_001318113; NM_001318114; NM_001318115; NM_001318116
	NM_001177691; NM_001177703; NM_016922; NM_001382290; NM_001382291
NP_001305032; NP_001305033; NP_001305034; NP_001305035; NP_001305036;
	NP_001305037; NP_001305038; NP_001305039; NP_001305040; NP_001305041; NP_001305042; NP_001305043; NP_001305044; NP_001305045; NP_004852
	NP_001171162; NP_001171174; NP_058618; NP_001369219; NP_001369220
	Wikidata
View/Edit Human	View/Edit Mouse

Galactosylceramide sulfotransferase is an enzyme that in humans is encoded by the GAL3ST1 gene.

Sulfonation, an important step in the metabolism of many drugs, xenobiotics, hormones, and neurotransmitters, is catalyzed by sulfotransferases. The product of this gene is galactosylceramide sulfotransferase which catalyzes the conversion between 3'-phosphoadenylylsulfate + a galactosylceramide to adenosine 3',5'-bisphosphate + galactosylceramide sulfate. Activity of this sulfotransferase is enhanced in renal cell carcinoma.