GAL3ST3

GAL3ST3
Identifiers
Aliases	GAL3ST3, GAL3ST-3, GAL3ST2, galactose-3-O-sulfotransferase 3
External IDs	OMIM: 608234; MGI: 3617843; HomoloGene: 57198; GeneCards: GAL3ST3; OMA:GAL3ST3 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	66,049,161 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	5,358,766 bp
RNA expression pattern
	Top expressed in
	gonad; ; left lobe of thyroid gland; ; right lobe of thyroid gland; ; caudate nucleus; ; putamen; ; right auricle of heart; ; nucleus accumbens; ; right hemisphere of cerebellum; ; right frontal lobe; ; prefrontal cortex;
	Top expressed in
	hippocampus proper; ; primary visual cortex; ; striatum of neuraxis; ; superior frontal gyrus; ; dentate gyrus of hippocampal formation granule cell; ; Cerebellum; ; cerebellar cortex; ; neural tube; ; Mesencephalon; ; olfactory bulb;
	More reference expression data
	n/a
Gene ontology
Molecular function	galactose 3-O-sulfotransferase activity; transferase activity; galactosylceramide sulfotransferase activity; proteoglycan sulfotransferase activity; 3'-phosphoadenosine 5'-phosphosulfate binding; carbohydrate binding;
Cellular component	integral component of membrane; Golgi cisterna membrane; Golgi apparatus; membrane;
Biological process	glycolipid biosynthetic process; sulfur compound metabolic process; poly-N-acetyllactosamine metabolic process; oligosaccharide metabolic process; proteoglycan biosynthetic process; monosaccharide metabolic process;
	Sources:Amigo / QuickGO
Orthologs
	89792
	545276
	ENSG00000175229
	ENSMUSG00000047658
	Q96A11
	P61315
	NM_033036
	NM_001024717
	NP_149025
	NP_001019888
	Wikidata
View/Edit Human	View/Edit Mouse

Galactose-3-O-sulfotransferase 3 is an enzyme that in humans is encoded by the GAL3ST3 gene.

This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate group to the 3' position of galactose in N-acetyllactosamine in both type 2 (Gal-beta-1-4GlcNAc-R) oligosaccharides and core-2-branched O-glycans, but not on type 1 or core-1-branched structures. This gene, which has also been referred to as GAL3ST2, is different from the GAL3ST2 gene located on chromosome 2 that encodes a related enzyme with distinct tissue distribution and substrate specificities, compared to galactose-3-O-sulfotransferase 3.