GAL3ST4

GAL3ST4
Identifiers
Aliases	GAL3ST4, GAL3ST-4, galactose-3-O-sulfotransferase 4
External IDs	OMIM: 608235; MGI: 1916254; HomoloGene: 11633; GeneCards: GAL3ST4; OMA:GAL3ST4 - orthologs
Gene location (Human)
Chr.	Chromosome 7 (human)
End	100,168,617 bp
Gene location (Mouse)
Chr.	Chromosome 5 (mouse)
End	138,271,102 bp
RNA expression pattern
	Top expressed in
	parotid gland; ; skin of abdomen; ; vulva; ; skin of leg; ; skin of thigh; ; thymus; ; nipple; ; ganglionic eminence; ; synovial membrane; ; endothelial cell;
	Top expressed in
	lip; ; esophagus; ; zone of skin; ; embryo; ; embryo; ; granulocyte; ; blastocyst; ; striatum of neuraxis; ; epiblast; ; genital tubercle;
	More reference expression data
	n/a
Gene ontology
Molecular function	galactose 3-O-sulfotransferase activity; transferase activity; galactosylceramide sulfotransferase activity; proteoglycan sulfotransferase activity; 3'-phosphoadenosine 5'-phosphosulfate binding;
Cellular component	integral component of membrane; Golgi cisterna membrane; Golgi apparatus; extracellular exosome; membrane;
Biological process	glycolipid biosynthetic process; sulfur compound metabolic process; cell-cell signaling; glycoprotein metabolic process; oligosaccharide metabolic process; proteoglycan biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	79690
	330217
	ENSG00000197093
	ENSMUSG00000075593
	Q96RP7
	n/a
	NM_024637
	NM_001033416; NM_001347507; NM_001361283
	NP_078913
	n/a
	Wikidata
View/Edit Human	View/Edit Mouse

Galactose-3-O-sulfotransferase 4 is an enzyme that in humans is encoded by the GAL3ST4 gene.

This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate to the C-3' position of galactose residues in O-linked glycoproteins. This enzyme is highly specific for core 1 structures, with asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc being good substrates.