GBA3

GBA3
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2E9L, 2E9M, 2JFE, 2ZOX, 3VKK
Identifiers
Aliases	GBA3, CBG, CBGL1, GLUC, KLRP, glucosylceramidase beta 3 (gene/pseudogene)
External IDs	OMIM: 606619; GeneCards: GBA3; OMA:GBA3 - orthologs
Gene location (Human)
Chr.	Chromosome 4 (human)
End	22,819,575 bp
RNA expression pattern
	Top expressed in
	jejunal mucosa; ; mucosa of ileum; ; duodenum; ; human kidney; ; liver; ; right lobe of liver; ; renal medulla; ; kidney tubule; ; buccal mucosa cell; ; testicle;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	beta-galactosidase activity; glycosylceramidase activity; hydrolase activity, hydrolyzing O-glycosyl compounds; beta-glucosidase activity; hydrolase activity; hydrolase activity, acting on glycosyl bonds; scopolin beta-glucosidase activity; glucosylceramidase activity; protein binding; galactosylceramidase activity;
Cellular component	cytoplasm; cytosol; catalytic complex;
Biological process	glycosylceramide catabolic process; metabolism; glycosphingolipid metabolic process; glycoside catabolic process; protein stabilization; cellular oligosaccharide catabolic process; positive regulation of exo-alpha-sialidase activity; carbohydrate metabolic process; glucosylceramide catabolic process; galactosylceramide catabolic process; beta-glucoside catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	57733
	n/a
	ENSG00000249948
	n/a
	Q9H227
	n/a
	NM_001128432; NM_001277225; NM_020973
	n/a
	NP_001121904; NP_001264154; NP_066024
	n/a
	Wikidata
View/Edit Human

Cytosolic beta-glucosidase, also known as cytosolic beta-glucosidase-like protein 1, is a beta-glucosidase (EC 3.2.1.21) enzyme that in humans is encoded by the GBA3 gene.