GBP2

GBP2
Identifiers
Aliases	GBP2, guanylate binding protein 2
External IDs	OMIM: 600412; MGI: 102772; HomoloGene: 10289; GeneCards: GBP2; OMA:GBP2 - orthologs
Gene location (Human)
Chr.	Chromosome 1 (human)
End	89,150,456 bp
Gene location (Mouse)
Chr.	Chromosome 3 (mouse)
End	142,343,769 bp
RNA expression pattern
	Top expressed in
	tendon of biceps brachii; ; Achilles tendon; ; monocyte; ; gastric mucosa; ; granulocyte; ; pericardium; ; muscle layer of sigmoid colon; ; blood; ; right adrenal gland; ; urethra;
	Top expressed in
	subcutaneous adipose tissue; ; mucous cell of stomach; ; submandibular gland; ; white adipose tissue; ; conjunctival fornix; ; right lung lobe; ; carotid body; ; tunica adventitia of aorta; ; mesenteric lymph nodes; ; iris;
	More reference expression data
	n/a
Gene ontology
Molecular function	nucleotide binding; GTP binding; protein binding; hydrolase activity; GTPase activity; protein homodimerization activity;
Cellular component	Golgi membrane; membrane; nucleoplasm; cytosol; actin cytoskeleton; nucleus; cytoplasm; Golgi apparatus; perinuclear region of cytoplasm; symbiont-containing vacuole membrane; cytoplasmic vesicle;
Biological process	type I interferon signaling pathway; immune response; interferon-gamma-mediated signaling pathway; protein localization to nucleus; cellular response to interferon-gamma; cellular response to interleukin-1; cellular response to tumor necrosis factor; defense response to protozoan; defense response to Gram-positive bacterium;
	Sources:Amigo / QuickGO
Orthologs
	2634
	14469
	ENSG00000162645
	ENSMUSG00000028270
	P32456
	Q9Z0E6
	NM_004120
	NM_010260
	NP_004111
	NP_034390
	Wikidata
View/Edit Human	View/Edit Mouse

Interferon-induced guanylate-binding protein 2 is a protein that in humans is encoded by the GBP2 gene. GBP2 is a gene related to the superfamily of large GTPases which can be induced mainly by interferon gamma.